The genomes of species from bacteria to Drosophila show unique biases for particular synonymous codons—varying triplet base pairs that code for the same amino acids—but it has been unclear if such ...

Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University led by Chen Peng from College of ...

Scientists have dreamt of rationally engineering microorganisms since the 1960s. Back then, while studying the lac operon in Escherichia coli, Francois Jacob and Jacques Monod proposed that cells ...

How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics. The genome of a protist has revealed a seemingly unique divergence in ...

Proteins are built by mixing and matching amino acids, but researchers want to create new functions by adding noncanonical amino acids (ncAAs). However, this process often requires complex whole ...