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For remission induction, dose reduction and avoidance of prolonged use of cyclophosphamide have been successfully implemented; the addition of plasma exchange has increased the rate of renal recovery ...

Patients with GCA or AAV were associated with an increased risk for hospitalization due to pneumonia compared with members of the general population.

Conjunctivitis or episcleritis and scleritis comprised the most common eye manifestations, while cataracts (11.7%) and visual ...

Anti-neutrophil cytoplasmic antibodies (ANCAs), such as those directed towards proteinase 3 (PR3) and myeloperoxidase (MPO), are associated with a distinct form of small-vessel vasculitis, known as ...

Cigarette smoking was associated with ANCA-associated vasculitis, particularly myeloperoxidase ANCA-positive vasculitis, according to data published in JAMA Internal Medicine. “We have an incomplete ...

Doctor talking to cancer patient A EULAR task force revised guidelines to reflect findings from randomized clinical trials that were published since the last update in 2016. A task force of the ...

Small studies have found that B-cell depletion with rituximab may be beneficial in refractory antineutrophil cytoplasmic antibody-associated (ANCA-associated) vasculitis, due to the presence of ...

A population-based study of Swedish adults found that ANCA-associated vasculitis is more prevalent among men than women. Despite a stable incidence of ANCA-associated vasculitis in southern Sweden, ...

Avacopan, which targets a receptor that attracts the cells that cause inflammation, was shown to be more effective at keeping patients in remission for a year than prednisone. A Phase 3 clinical trial ...

Mycophenolate mofetil (CellCept) was as effective as cyclophosphamide for remission induction in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, Japanese researchers reported. In a ...

In patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis treated with rituximab, risk factors for relapse differed by treatment phase; musculoskeletal involvement was ...