Animal models have long shaped how biomedical research is conducted. They have influenced how diseases are studied, how ...

Testing new treatments in other animals can help us spot complications or potential pitfalls, but the results don’t always ...

Due to advancements in genetic engineering, small animal models are continuing to change in response to market needs. Model developers strive to better reflect the role of this important asset in both ...

The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...

In this free webinar, learn how modeling and simulation can help navigate the Animal Rule in drug development. Attendees will gain insight into when the Animal Rule is appropriate to use for drug ...

Expert Rev Clin Pharmacol. 2012;5(6):667-676. Endophenotypes are defined as measurable intermediate disease features that bridge the gap between overt manifestations of schizophrenia and underlying ...

A perspective in the Journal of the Royal Society Interface argues that advances in AI, sensing technologies and modeling are ...

Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...