A research team led by investigators at McMaster University has identified an axonal guidance signaling pathway that cancer cells use to infiltrate the brain. The combined results of preclinical in ...

Neurotrophins are essential proteins that support the growth, survival, and differentiation of neurons. Among these, brain-derived neurotrophic factor (BDNF) plays a crucial role in neuronal signaling ...

A new pathway that is used by cancer cells to infiltrate the brain has been discovered by a team of Canadian and American research groups led by the Singh Lab at McMaster University. The research also ...

BUFFALO, N.Y. — A hallmark of Parkinson’s disease is the buildup of Lewy bodies — misfolded clumps of the protein known as alpha-synuclein. Long before Lewy bodies form, alpha-synuclein can interfere ...

Researchers have uncovered a surprising molecular chain reaction in the brain that may play a role in some forms of autism.

Within the human brain, movement is coordinated by a brain region called the striatum, which sends instructions to motor neurons in the brain. Those instructions are conveyed by two pathways, one that ...