Pasca Lab specializes in growing three-dimensional organoid models from reprogrammed stem cells, which capture molecular changes during fetal brain-like development. Because the human brain cannot be ...

Researchers have found hundreds of metabolic enzymes attached to human DNA inside the cell nucleus. Different tissues and cancers show unique patterns of these enzymes, forming a “nuclear metabolic ...

In some mammals, the timing of the normally continuous embryonic development can be altered to improve the chances of survival for both the embryo and the mother. This mechanism to temporarily slow ...

After more than a decade of research, scientists have discovered the natural mechanism behind a novel form of cell death ...

Mitochondria are essential for cell survival, repair, and adaptation. Not only do they generate most of the energy needed ...

A research team has conducted a study exploring the role of the mannose pathway in regulating cell fate decisions in low glucose environments. Their work may hold potential for novel therapeutic ...

Dendritic cells (DCs) are among the first immune sentinels to detect viruses, bacteria, or other challenges. These specialized messengers alert T cells while orchestrating either a measured calm or a ...

A new study led by researchers at Adelaide University and published in Science Advances reveals why some cancers can grow and survive in the body, while others cannot. It turns out that intense ...

Researchers have transplanted healthy mitochondria into brain cells and animal models of neurodegeneration, reporting improved energy output, reduced cell death, and temporary recovery of motor ...