A metabolic enzyme studied for over seven decades has a hidden second function—it can unwind RNA and promote cell cycle progression, an additional function beyond its role in energy production, ...
Researchers at the University of Illinois Urbana-Champaign have built a computer simulation that tracks the entire life cycle of a living cell in four dimensions, capturing how the genetically minimal ...
Study: Characterizing the evolutionary dynamics of cancer proliferation in single-cell clones with SPRINTER. Image Credit: Anusorn Nakdee/Shutterstock.com In a recent study published in Nature ...
By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell ...
A metabolic enzyme also binds and unwinds RNA to promote translation of cell cycle genes. This dual role links energy status ...
A simulated cell in the early stages of division. Left half shows membrane (green cubes), and ribosomes (yellow/purple) interwoven through in the cell’s chromosome (red). Right side shows all the ...
New research from Dana-Farber Cancer Institute shows that a new class of drug results in cell death in cancers, such as small cell lung cancer, with a disabled quality control cell cycle checkpoint ...
Figure 6. Senescent heterogeneity model based on DNA content. Compared to G1-arrested cells, G2-arrested senescent cells express higher levels of senescence-associated markers, secrete more IL-6, and ...
A newly developed single-cell metabolomics approach enabled researchers to measure the metabolites produced by individual ...