DNA synthesis is vital to several processes in biopharmaceutical innovation, including the development of gene therapies, CRISPR gene editing, antisense oligonucleotides and RNA therapies. The need ...

RNA drugs are the next frontier of medicine, but manufacturing them requires an expensive and labor-intensive process that limits production and produces metric tons of toxic chemical waste.

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and ...

Green synthesis and catalytic methods are revolutionising organic chemistry by offering sustainable alternatives to traditional synthetic processes. These approaches prioritise the use of ...

A team of chemists has unveiled a novel method to simplify the synthesis of piperidines, a key structural component in many pharmaceuticals. The study combines biocatalytic carbon-hydrogen oxidation ...

Coupling reactions are among the most transformative tools in organic chemistry, enabling the formation of crucial chemical bonds in pharmaceuticals, agrochemicals, and advanced materials. Since their ...

The article provides a comprehensive review of the current progress and future prospects of high-pressure-driven chemical synthesis, offering constructive guidance for the design and development of ...

Chemistry is all around us. From the widespread production of global food supplies to the metabolism that fuels the tiniest of microorganisms, everything in our surroundings is produced and controlled ...

This module explores the synthesis of amines with a focus on the reductive amination reaction. Numerous examples from the discovery and commercial manufacturing of pharmaceuticals are included. After ...

Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound.

Researchers have demonstrated a halogen-free method for building ultra-long carbon nanoribbons on copper surfaces, removing ...