Comparative effectiveness research (CER) seeks to assist consumers, clinicians, purchasers, and policy makers to make informed decisions to improve health care at both the individual and population ...

The public may comment on the Patient-Centered Outcomes Research Institute's draft methodology report. As many readers know, PCORI is a public-private entity created in the Affordable Care Act to fund ...

There is an increasing need for reliable information on the relative value of medical interventions to assist decision making on both the individual and public health levels; addressing this need is ...

Clinical trials that are embedded into usual care have the potential to yield outcomes of great relevance to the institutions where they are performed and at the same time to yield information that ...

John Zalcberg undertook this work while on sabbatical at the National Institute for Clinical Studies but other than in kind support, he did not receive funds from that organisation. The evidence ...