Cycloaddition reactions represent a cornerstone of synthetic organic chemistry, facilitating the formation of cyclic structures through concerted pericyclic processes. Traditionally explained via ...

Cycloaddition reactions are an efficient strategy for constructing cyclic compounds that are important building blocks for other chemicals. In these processes, π-electrons from different unsaturated ...

A new three-way bond-breaking and making mechanism makes the synthesis of five-membered rings easier than before.

Automated reaction path search method predicts accurate stereochemistry of pericyclic reactions using only target molecule structure. Researchers at the Institute for Chemical Reaction Design and ...