Background Monogenic disorders are a major cause of fetal structural anomalies. Most genetic diagnoses involve de novo, biallelic or X linked variants; however, inherited variants in autosomal ...

The systematic review provides compelling evidence that genetic factors play a significant role in the development of lower urinary tract symptoms (LUTS) in adults, suggesting that genetic ...

For more than a century, Mendelian genetics has shaped how we think about inheritance: one gene, one trait. It is a model that still echoes through textbooks—and one that is increasingly reaching its ...

Researchers have found that the severity of autism symptoms, rather than the diagnosis itself, is linked to patterns of brain connectivity associated with genes connected to autism and ADHD.

Hundreds of genes have been linked to autism, but knowing which ones matter most has been a challenge. Researchers at the University of Aberdeen combined data from thousands of developing human brain ...