Innate immune sensors—known as pattern recognition receptors (PRRs)—detect specific molecular components of bacterial or ...

Virus-associated cancers are a significant and persistent global health challenge, providing unique insight into the relationship between chronic infection ...

Scientists discover how innate immunity envelops bacteria. The protein GBP1 is a vital component of our body's natural defense against pathogens. This substance fights against bacteria and parasites ...

The immune system can work in two ways: the innate immune system reacts to any foreign invaders that are identified by immune cells that look for such pathogens; but the acquired or adaptive immune ...

When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

Discovered in 1964 by Anthony Epstein, Yvonne Barr, and Bert Achong, the Epstein-Barr virus (EBV) has intrigued tumor virologists due to its unique behavior. Typically, EBV establishes a lifelong, ...

Secondary infections caused by bacteria or viruses during hospital care remain a long-standing global challenge, despite advances in modern medicine. In particular, mixed bacterial–viral infections in ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

Our immune system is divided into two main branches: innate and adaptive. Innate immune cells act as a first line of defense, quickly responding to invaders, while adaptive immune cells take a longer ...

Researchers have shown that innate immune training, also known as trained immunity (TRIM), leads to aggravated bone loss in experimental models of periodontitis and inflammatory arthritis. Clinical ...