Intrathecal chemotherapy is a form of cancer treatment in which a healthcare professional injects chemotherapy drugs into the cerebrospinal fluid (CSF). This colorless fluid surrounds the brain and ...

Panelists discuss how intrathecal delivery of onasemnogene abeparvovec in the STEER study demonstrates statistically significant motor function improvements in older patients with SMA (ages 2-18 years ...

Chemotherapy medications can come in many forms and types (oral, injectable, inhaled, etc.). If you need medication, the type that’s right for you will depend on how the medication works and the ...

A pair of clinical data sets gives Novartis confidence in a new formulation of the company’s gene therapy Zolgensma for the treatment of older patients with spinal muscular atrophy (SMA). Among SMA ...

PHILADELPHIA (WPVI) -- Pain is one of the most common problems for cancer patients. They often struggle to find relief or with side effects from the powerful narcotics often used for pain. There's an ...

A novel indwelling subcutaneous intrathecal catheter circumvented the complex spine anatomy of patients with spinal muscular atrophy (SMA), a challenge when giving nusinersen via intrathecal injection ...

More than three years after Novartis’ plan for a speedy approval for intrathecal Zolgensma was thwarted by an FDA requirement for a pivotal phase 3 trial, the company is back with a positive readout ...

Baclofen 50mcg/mL, 500mcg/mL, 2000mcg/mL; for intrathecal inj; preservative-free. <4yrs: not established. ≥4yrs: Give test dose 1 st by intrathecal inj via spinal catheter or lumbar puncture (see full ...

Sometimes cancer cells are able to cross into the fluid that surrounds and protects your brain and spinal cord. Cancer drugs you take by mouth or through a vein can’t get through as easily.