Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.

A new understanding of how drugs are taken in by cells could impact the way drugs are administered to patients. In an Aug. 30 study published in Nature that details structural changes of the Transient ...

Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through blood vessels and bodily fluids: special proteins that keep their ...

The fibroblast growth factor (FGF) family, together with their intracellular homologous factors, represents a critical nexus in the regulation of ion channels across multiple physiological systems.

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge. Now, researchers have ...

Cells send electrical impulses throughout the body, but electrophysiologists struggled to tune into these signals until the patch clamp technique was developed. Although biophysicist Bernard Katz from ...

Researchers have discovered how an ion channel in the brain's neurons has a kind of 'molecular memory', which contributes to the formation and preservation of lifelong memories. The researchers have ...

A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a study led by researchers at Weill ...

Researchers decipher the function of an ion channel involved in cellular degradation processes and create new possibilities for Parkinson’s therapies.