A team of US researchers has gained new insights into how large protein molecules consistently fold themselves into useful shapes. Using a new approach to fluorescence microscopy, Hoi Sung Chung and ...

Volumetric fluorescence microscopy is an indispensable tool for comprehensive studies of cells and organs. Since the specimens are inherently three-dimensional (3D), the optimal imaging system should ...

In PhotoniX, researchers report a self-supervised deep learning method that denoises dynamic fluorescence images in vivo without requiring clean training data. The figure shows in vivo venule images ...

(A–C) Representative images reconstructed by conventional method (left) and new method (right) of microtubules, nuclear pore complexes and F-actin samples. The regions enclosed by the white boxes are ...

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

In recent years, fluorescence quenching microscopy (FQM) 1-3 has emerged as a viable technique that allows for the swift, cost-effective, and accurate imaging of two-dimensional (2D) materials like ...

What is Structured Illumination Microscopy? Structured Illumination Microscopy (SIM) is a super-resolution fluorescence microscopy technique that allows for imaging beyond the diffraction limit of ...

In a recent review article published in the journal Microscopy Research & Technique, researchers focused on the integration of DL into optical microscopy, exploring its application in image ...

Researchers commonly employ fluorescence microscopy to characterize molecular, cellular, and developmental processes in depth. Despite its benefits, scientists can face challenges when imaging their ...