Notification: The Recombinant Protein Production and Characterization (RPPC) Core has undergone reorganization as of January 2026. The previous Macromolecular X-Ray Crystallography Core has been ...

Pichia pastoris has emerged as a leading eukaryotic host for recombinant protein production, owing to its ability to perform complex post-translational modifications and grow to high cell densities ...

Immobilized metal affinity chromatography (IMAC) is a reliable method for isolation of recombinant protein following over-expression in Escherichia coli. The polyhistidine tag (6–10 consecutive amino ...

Proteins are bio-macromolecules with a range of functionalities as a result of complex higher-order structures. As the end product of the “central dogma” in biology, proteins are considered the key ...

Creating recombinant proteins has become much easier over the past few decades. However, those with the skills to do design such constructs are usually limited to the biochemists who study proteins.

The enteric bacterium Escherichia coli is one of the most extensively used prokaryotic organisms for genetic manipulations and for the industrial production of proteins of therapeutic or commercial ...

Many proteins of interest are difficult to obtain, so it is important to establish sources that could potentially provide researchers with an unlimited supply of proteins. Recombinant protein ...

The clinical diagnostic industry is on the verge of a recombinant protein revolution. Recombinants have been available for decades and have served some sectors of diagnostics quite well, but they have ...

MammalExpress increases the efficiency and reduces the cost of producing recombinant proteins in mammalian cells. Recombinant proteins are proteins produced by genetic engineering. They are widely ...

Proteins are the fundamental building blocks of life, and they are the essential products of molecular biology’s core dogma. Proteins play a variety of roles in the body, including catalyzing ...

BERKELEY, CA – A new way to direct chemical modifications to specific sites on recombinant proteins – including the monoclonal antibodies so important in the pharmaceutical industry – has been ...