A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that ...

Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have ...

Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have uncovered a critical mechanism that enables gastric cancer to spread to ...

A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast ...

Pro-inflammatory M1 macrophages involved in immune responses accelerate the progression of melanoma through the extracellular ...

A number of recent trials have explored potential strategies for using immunotherapy in chronic lymphocytic leukemia (CLL). The authors explained that while molecularly targeted therapies like Bruton ...

A new study has given leukemia researchers a powerful new dataset and collection of analytical methods—and a starting point for future research. One common treatment for leukemia is hematopoietic stem ...

MILAN — Is chronic lymphocytic leukemia (CLL) progression primarily driven by genetic mutations or by external cues from the tumor microenvironment? Despite major strides in targeted therapies, CLL ...

As treacherous as it is complex, the tumor microenvironment (TME) is composed of different cell types that produce an abundance of cross-talking molecules, extracellular vesicles, and metabolites. All ...

The tumor microenvironment is a battleground where infiltrating immune cells either subdue or promote a cancer, all while cancer cells try to dampen the body’s defenses. 1,2 Scientists have studied ...