Chronic disease research increasingly points to the centrality of metabolic remodeling and mitochondrial dysfunction in dictating disease onset, severity, ...

Mitochondria are essential organelles that drive energy production, regulate apoptosis and orchestrate metabolic signalling within cells. Their dynamic nature underpins processes as diverse as ATP ...

Almost every American has some degree of metabolic dysfunction — at least that’s what President Trump’s nominee for surgeon general would say. Dr. Casey Means, a graduate of the Stanford School of ...

More than half of people with mitochondrial disease can be diagnosed via genomic sequencing, a finding that will revolutionise care for families, according to a new study. And the Melbourne ...

Mitochondria are well known as the powerhouses of the cell. These crucial, energy generating organelles even have their own little genomes, and make their own proteins. Mutations in mitochondrial DNA ...

Mitochondrial DNA has long been treated as a workhorse record of cellular history, but new research suggests it also hides a subtle and previously overlooked form of damage. By uncovering this cryptic ...

Researchers uncover how cells internalize transplanted mitochondria, paving the way for new energy-restoring therapies for Parkinson’s and Alzheimer’s.

In most cases, the damage is linked to mutations in the OPA1 gene, which interfere with mitochondrial function (how cells make energy and stay healthy). New research led by Thomas Schwarz, Ph.D., and ...

Patients with rare mitochondrial diseases already face a host of serious health issues, from muscle weakness to neurological problems and heart conditions. But one of their most life-threatening ...

Millions of people worldwide live with mitochondrial diseases. These are inherited conditions that make it hard for the body’s cells to produce energy. For a long time, patients had few options ...

New research profiles mitochondrial circular RNAs in Peripheral Blood Mononuclear Cells (PBMCs) from young and old human ...