Nature

Both Normal Memory Counts and Decreased Naive Cells Favor Intrinsic Defect Over Early Senescence of Down Syndrome T Lymphocytes

An extra 3 mL of EDTA blood and 7 mL of blood without additive was drawn from 95 noninstitutionalized DS children (49 males; mean age, 7 y; range, 1–20) visiting the Jeroen Bosch Hospital, ...
Nature

Analysis of gene expression in normal and malignant lymphocytes using the Lymphochip cDNA microarray

Genome-wide knowledge of gene expression in cancer cells promises to illuminate many aspects of their clinical behaviour. We have begun a study of gene expression in lymphoid malignancies by ...
ascopubs.org

In vitro and in vivo studies of human lymphocytes genetically engineered to express T cell receptors that recognize a p53 antigenic epitope

Toll-like receptor 7 agonist induces apoptosis of human B-lineage acute lymphocytic leukemia cells in vitro and in vivo No significant financial relationships to disclose. This is an ASCO Meeting ...