CI: Confidence interval; HbA1c: Glycated hemoglobin; I: Interventional study; IR: Insulin resistance; L: Longitudinal study; OR: Odds ratio; TOC: Total osteocalcin; X ...
Glu-OCN is secreted by osteoblasts and then undergoes γ-carboxylation at glutamic acid residues at positions 17, 21, and 24, a reaction catalyzed by γ-glutamyl carboxylase (GGCX) in a vitamin ...
Osteocalcin (OCN) is a multifunctional bone-derived hormone that modulates numerous physiological activities. OCN can cross the blood brain barrier (BBB) and thus play critical roles in neuronal and ...
Osteocalcin (OCN) is a multifunctional bone-derived hormone that modulates numerous physiological activities. OCN can cross the blood brain barrier (BBB) and thus play critical roles in neuronal and ...
Experiments in mice and observations in humans have suggested the bone protein osteocalcin acts as a hormone regulating, among other things, metabolism, fertility, exercise capacity and acute stress.