Although the pathophysiology of mesangial cells has long been considered to be the major factor in the development of glomerulosclerosis in type 1 or type 2 diabetes, more recent evidence suggests ...

BUFFALO, N.Y. — In the early stages of kidney disease, a specialized type of kidney cell called the podocyte undergoes damaging changes in both its structure and function. Those changes are key ...

BUFFALO, NY-August 8, 2023 – A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, “Inhibiting ...

Podocytes are a terminally differentiated cell type located in the glomerulus. Podocyte damage and the subsequent dysregulation of podocyte proteins have been implicated in various kidney disorders.

As one of the major targets of Covid-19, infection in the kidneys can led to significant complications associated with kidney disease, as well as kidney failure. Kidney damage can occur even in those ...

Genetic mutations which cause a debilitating hereditary kidney disease affecting children and young adults have been fixed in patient-derived kidney cells using a potentially game-changing DNA ...

Chronic kidney disease can quietly reshape a life long before the first lab test comes back abnormal. More than 700 million ...

Acute kidney injury (AKI) often occurs as a result of ischemia, which is a condition in which blood flow to part of the body is restricted, depriving tissues of oxygen and nutrients. This damage is ...

Chronic kidney disease (CKD) affects more than 10% of the global population and is expected to become the fifth leading cause of death worldwide within the next two decades. Perhaps surprisingly, ...