Reducing RAD23A levels helped nerve cells better handle toxic TDP-43 protein clumps, improving survival and function in an ...

Targeted protein degradation presents a promising strategy to address antimicrobial resistance, focusing on innovative ...

Northwestern Medicine scientists have zeroed in on a cellular gatekeeper that may hold promise for treating abnormal protein ...

Researchers have developed smart nanoparticles that can seek out and destroy disease-causing proteins the body can’t normally eliminate. Unlike traditional drugs, these particles can reach ...

Targeted protein degradation (TPD) is transforming drug discovery by leveraging the cell’s natural protein disposal systems to eliminate disease-causing proteins. Innovators are making rapid and ...

Maintaining cellular order is a major logistical challenge: Individual mammalian cells contain billions of protein molecules, ...