PERPHENAZINE and other phenothiazines are widely used for their potent antiemetic and tranquilizing properties. Various toxic reactions to these agents have been reported. To enhance the therapeutic ...

AS the so-called "tranquilizing drugs" continue to increase in use and misuse, the physician will become more aware of the alarming side reactions that may be inherent in their pharmacologic formulas.

The approval of Osmolex ER was based on bioavailability studies comparing Osmolex ER to immediate-release amantadine. Osmotica announced that the Food and Drug Administration (FDA) has approved ...

Pharmacogenomics is yet to fulfill its promise of manifestly altering clinical medicine. As one example, a predictive test for tardive dyskinesia (TD) (an adverse drug reaction consequent to ...

EPSs are serious, debilitating and stigmatizing adverse effects that frequently require additional pharmacotherapy. 3 The two types of EPSs are as follows: early acute EPS, which most often develops ...