Taste, pain, or response to stress -- nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers have uncovered the ...
Morning Overview on MSN
Scientists watch drug molecules hit cell receptors in real time
Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...
Hitting targets embedded within the cell membrane has long been difficult for drug developers due to the membrane's challenging biochemical properties. Now, chemists have demonstrated new ...
Receptor proteins, expressed on the cell surface or within the cell, bind to different signaling molecules, known as ligands, initiating cellular responses. Taste receptors, expressed in oral tissues, ...
Histamine is widely known for its role in allergic reactions but also functions as a key neurotransmitter in the brain, where ...
A new study found that a single mutation to the hemagglutinin protein of an H5N1 virus isolated from a dairy worker in Texas this spring switched the protein’s binding specificity from avian- to human ...
An unexpected find shows that sweet-sensing receptors also help epithelial cells in Drosophila larvae stay alive amid proteotoxic stress. While combing through a list of genes that are differently ...
For the first time, researchers have determined how a human olfactory receptor captures an airborne scent molecule, the pivotal chemical event that triggers our sense of smell. Whether it evokes roses ...
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