Poor solubility remains a big issue for drug development and, as such, is driving innovation in approaches and use of novel technologies to help overcome the associated challenges. Increasingly, ...
Modern methods and modeling offer a better way to understand solubility issues and solve today’s complex formulation challenges. Poor solubility is an ongoing challenge in pharmaceutical development.
Determining aqueous compound solubility has become an essential tool in the early stages of the drug discovery process. Solubility of a compound is important in the Biopharmaceutics Classification ...
Researchers have developed a new method for the accurate determination of the water content of water-soluble compounds. This plays a significant role in various areas, including determining drug ...
Scientists from the Skoltech Center for Energy Science and Technology (CEST) and the Institute for Problems of Chemical Physics of Russian Academy of Sciences in collaboration with researchers from ...
About 40% of marketed drugs are thought to be poorly water soluble. Development efforts might have to be redoubled, however, because between 70 and 90% of drug candidates in the pipeline are believed ...
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