A new study has uncovered how an exceptionally scarce protein can orchestrate the assembly of large‑scale gene-silencing ...

Single-molecule imaging shows that three CBX2 protein molecules can seed Polycomb condensates that silence genes in stem ...

Thyroid development represents a complex orchestration of cellular migration, differentiation and folliculogenesis, all of which are tightly regulated by an interplay of signalling pathways and ...

All cells in the body arise from a single fertilized egg. From this single origin, various specialized cells with widely differing tasks evolve through a process called cellular differentiation.

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

There is a high unmet need for accessible, affordable, and high-quality fertility care, as approximately 1 in 6 people are affected by infertility worldwide. While meiotic failure is a major cause of ...

The mechanism for muscle stem cells repair could inspire therapeutics for muscle loss caused by injury, aging and weight-loss ...