Monica MacDonald is an alumna whose dissertation research was focused on natural product biosynthesis and protein structure-function relationships.

A research team reports that advances in protein design—especially when combined with artificial intelligence—are rapidly ...

Yuan He aims to understand how cells read and repair their genomes. His research encompasses two primary areas: transcription, in which genetic information is copied from DNA into messenger RNA, and ...

Cryo-electron microscopy (cryo-EM) has revolutionalized our understanding of the intricate molecular machinery that governs life. It has elucidated the three-dimensional (3D) structure of biological ...

Two key protein structures in the body are being visualized for the first time, thanks in part to the latest technology in the University of Cincinnati’s Center for Advanced Structural Biology — ...

Over the past decade, structural biology has been profoundly transformed by advances in computational power, algorithmic ...

Despite decades of study, a pharmacopoeia of medicines, and untold millions in pharmaceutical research, heart disease remains the leading cause of death around the world. Excess cholesterol in ...

Structural biology is used to understand the three-dimensional shape of biological molecules and how their shape enables them to function both inside and outside of cells. Furthermore, the ...

A microscopic image shows small red centers connected by networks of branched and straight filaments. The team mixed purified actin monomers with precise concentrations of two nucleation-promoting ...