Study reveals potential therapeutic target for treating glaucoma

Researchers have identified a metabolically sensitive cell subtype in the eye's drainage system which shows early signs of ...
eLife

Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment

Single-cell transcriptomics identifies three discrete mouse trabecular meshwork subtypes and demonstrates that an Lmx1b glaucoma mutation drives mitochondrial dysfunction and elevated intraocular ...
Ophthalmology Times

Q&A: What’s in the glaucoma treatment pipeline?

Prostaglandin analogues, such as latanoprost and bimatoprost, are the go-to therapies for glaucoma therapy. They continue to ...
EurekAlert!

‘Eye-on-a-chip’ reveals trigger for steroid-induced glaucoma

Immunofluorescence staining shows the layers of trabecular meshwork (red) and Schlemm’s canal endothelium (yellow) cells in a 3D “eye-on-a-chip” platform that mimics the flow of ocular fluids. The eye ...
Healio

Should MIGS be considered first-line therapy over eye drops?

Please provide your email address to receive an email when new articles are posted on . “It is essential for researchers and industry to continue developing innovative therapeutic options that are ...
EurekAlert!

Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues

Schematic diagram illustrating possible mechanisms of APOE in trabecular meshwork degeneration with aging. The study delves into the age-related changes in the trabecular meshwork (TM) of macaques, ...