Over the last three decades, scientists have devised molecular shuttles that slip enzymes, antibodies, and other molecules into the central nervous system (CNS) by attaching them to the transferrin ...

This new article publication from Acta Pharmaceutica Sinica B, discusses a transferrin receptor-targeted immunostimulant for photodynamic immunotherapy against metastatic tumors through β-catenin/CREB ...

Duetta is a highly sensitive spectrofluorometer that can be used to measure transferrin at very low concentrations. By ...

Iron intake and soluble transferrin receptor were positively associated with insulin resistance, whereas serum iron and transferrin receptor were negatively associated. Disturbances in iron metabolism ...

In an important step toward more effective gene therapies for brain diseases, researchers have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier ...

A Denali Therapeutics drug for the rare enzyme deficiency Hunter syndrome is still in pivotal testing, but the company has guidance from the FDA on a pathway to get this therapy to the market sooner.

Each cell is separated from its environment by a membrane that protects the cell from the outside environment. However, this barrier can be overcome by certain chemicals that sustain the basic ...