Elevated tryptophan metabolism correlates with improved csDMARD response, reduced inflammation, and better clinical outcomes in rheumatoid arthritis patients. Multiomics analysis identified ...

As people grow older, the same brain chemistry that once supported sharp thinking and stable mood can quietly start to work against them. A new wave of research is revealing how a single amino acid, ...

Tryptophan does far more than help us sleep—it fuels brain chemistry, energy production, and mood-regulating neurotransmitters. But as the brain ages or develops neurological disease, this delicate ...

Background Both host and microbe metabolism of tryptophan (Trp) is altered in diabetes; however, the molecular mechanisms are ...

Microbiome dysbiosis—changes in the composition of gut microbes that alter the metabolites present—has long been implicated in playing a causative role in the pathophysiology of autism spectrum ...

Scientists have discovered that an imbalance of certain chemicals in the brain could help explain why teenage girls are at greater risk of depression than boys. Specifically, researchers claim to have ...

This review illustrates amino acid metabolic reprogramming in breast cancer, highlighting its role in tumor progression and clinical applications, including diagnostic imaging, targeted therapies, ...