Cluster randomized trials (CRTs) represent a pivotal design in evaluating public health and clinical interventions where individuals are grouped into clusters (such as schools, hospitals or ...

Twice-yearly mass distribution of azithromycin to children is a promising intervention to reduce childhood mortality in sub-Saharan Africa. The World Health Organization recommended restricting ...

Evidence-based practices for reducing opioid-related overdose deaths include overdose education and naloxone distribution, the use of medications for the treatment of opioid use disorder, and ...

Impact of a collaborative care-based symptom intervention model on chemotherapy adherence in patients with breast cancer. Electronic patient-reported outcomes with vital sign monitoring versus usual ...

Cluster RCT finds mobile instant messaging exercise reminders did not significantly boost lab-verified smoking cessation at 6 months.

A phase 2/3 study of fianlimab plus cemiplimab versus cemiplimab in patients with advanced non-small cell lung cancer with tumors expressing PD-L1 ≥50%. LUNAR-2: Pivotal, randomized, open-label study ...

While insecticide-based interventions help reduce malaria's disease burden, rising resistance and evolving behavior by the malaria-spreading anopheles mosquito threaten that progress. In a ...

In a pragmatic cluster non-randomized trial, Alexandra Kulinkina and colleagues investigate the effectiveness of a clinical decision support algorithm ...

Objective To investigate if a combination of an online and onsite implementation strategy was superior to an online-only strategy in enhancing the use of an injury prevention exercise programme (IPEP) ...

Correspondence to Dr Juliana S Oliveira, Sydney Musculoskeletal Health, The University of Sydney, Sydney, New South Wales 2050, Australia; juliana.oliveira{at}sydney.edu.au Intervention Intervention ...