A cell's secrets can be divulged by its surface, decorated with tens to hundreds of thousands of molecules that help immune cells determine friend from foe. Some of those protruding molecules are ...

Normally, the immune system is able to differentiate between healthy and abnormal cells. Peptides, fragments created by the synthesis and breakdown of proteins inside each cell, are presented on the ...

A new approach, which mimics the physical forces exerted by immune cells as they crawl over host cells, could help scientists develop more effective cancer immunotherapies. A cell's secrets can be ...

Study introduces TRACeR-I, a protein platform with broad HLA compatibility, paving the way for advanced immune response engineering and disease-specific targeting. Study: Targeting peptide antigens ...

Scientists have created a pipeline for identifying, prioritizing and evaluating potential tumor antigens for the fast generation of cancer vaccines, according to a new report. The new approach could ...

Within each individual’s immune system is a unique repertoire of billions of T cells patrolling the body to uncover and eliminate foreign threats. Yet this army is not foolproof and can miss the ...

TransCon IL-2 β/γ, a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 analog, demonstrates improved pharmacokinetics and profound expansion of cytotoxic immune cells in ...

Researchers from MIT and Dana-Farber Cancer Institute have discovered that a class of peptides expressed in pancreatic cancer cells could be a promising target for T-cell therapies and other ...

Breast cancer phenotype in patients with hereditary gene mutations other than BRCA1 and BRCA2. This is an ASCO Meeting Abstract from the 2017 ASCO Annual Meeting I. This abstract does not include a ...

A novel prioritisation pipeline and ‘plug-and-play’ vaccine technology opens up the possibility of rapidly generating tailored cancer vaccines for clinical use Scientists have created a pipeline for ...