This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

Earendil Labs, a global leader in AI-driven research and development of next-generation biologics therapeutics, today announced a strategic collaboration with Sanofi to apply Earendil's discovery ...

If nonliving materials can produce rich, organized mixtures of organic molecules, then the traditional signs we use to ...

This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...

Protein aggregation exhibits a dual role in biology, especially in neural systems. While pathogenic aggregates of proteins such as Aβ, tau, and α-synuclein ...

Abstract: Protein-protein interaction (PPI) networks play a vital role in the functional organization of cellular systems. Recurring subgraph patterns with these networks, known as motif structures, ...

Pavle Jeremić, Founder and CEO of Aether, is a scientist-entrepreneur focused on turning advanced research into real-world industrial impact. With a background in biomolecular engineering and early ...

Artificial intelligence has just helped virologists pull off something that used to take years of trial and error: crippling a virus by changing a single molecular contact point. Instead of screening ...

As bispecifics, ADCs, protein degraders, and AI-designed mini-proteins move into the clinic, discovery teams face a new bottleneck: engineering and producing molecules whose complexity challenges ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Machine learning has proven to be very powerful for predicting mutation effects in ...