Alzheimer's disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older. The disease has proven difficult to develop new treatments for, and available ...

Researchers have shown that restoring youthful levels of a telomerase subunit can significantly alleviate aging signs in models, potentially impacting age-related diseases like Alzheimer’s and cancer.

Over the last few years it has become clear that mitochondria are not only the powerhouses of the cells, having their sole function in producing ATP. Proteome-analyses of mitochondria from different ...

On June 5, 1981, national health experts published accounts of a strange infection circulating around Los Angeles. The U.S. Centers for Disease Control and Prevention (CDC) reported on that day that, ...

A recent discovery reveals that human cells can transcribe RNA sequences into DNA, challenging a central principle in biology. In a discovery that challenges long-held dogma in biology, researchers ...

1 Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland 2 Department of Computer ...

RTX is a reverse transcriptase evolved in vitro from the B family DNA polymerase KOD. Structural analyses of RTX in complex with either a DNA duplex or an RNA–DNA hybrid and comparison with the apo, ...

Objective— The enzyme telomerase and its catalytic subunit the telomerase reverse transcriptase (TERT) are important for maintenance of telomere length in the nucleus. Recent studies provided evidence ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...