A team from University of Toronto Engineering is the first to synthesize long noncoding RNA (lncRNA) outside the cell — a new approach to drug discovery that has already yielded some ...

The code base for our work on improving the performance of sequence-to-expression models for making individual-specific gene expression predictions by fine-tuning them on personal genome and ...

Why do some tumors spread while others remain localized? The mechanisms governing the metastatic potential of tumor cells remain largely unknown—yet understanding this is crucial for optimizing ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics—meticulously placed chemical tags that influence which genes are expressed in ...

A daily glass of orange juice may do more than refresh; it can fine-tune thousands of genes tied to blood pressure and metabolism, with the benefits varying depending on your body weight. Study: A ...

Precision Treatment of Patients With GI Cancer Using Pre-emptive DPYD Genotyping/Phenotyping Plus Pharmacokinetic-Guided Dosing of 5-Fluorouracil Primary PCa biopsy samples underwent ...

Outcomes of young-onset colorectal cancer vs late-onset colorectal cancer patients on phase 1 matched and non-matched therapies. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I.

(A) Selected human single-cell transcriptome profiles from HCL and other public datasets were utilized to train and validate gPRINT. The human single-cell data encompasses 159,302 cells from 26 ...

IRVINE, Calif. & AMSTERDAM--(BUSINESS WIRE)--Agendia®, Inc., today announced that new data from its ongoing FLEX Study will be presented at the upcoming ESMO Breast Cancer 2025 congress taking place ...

Real-world analysis shows BluePrint® identifies chemotherapy-sensitive Basal-type tumors among MammaPrint® High Risk HR+ HER2- breast cancers, supporting more personalized treatment strategies IRVINE, ...