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Everyone wants to kill cancer, but almost nobody talks about how cancer actually grows and survives. Cancer growth isn’t random. It uses organized metabolic and signaling pathways to stay alive, divide, and spread. Here are the top 10 growth and survival pathways cancer uses: 1️⃣ Glycolysis / Warburg Effect – Cancer ferments glucose into lactate at a higher rate to fuel rapid growth. 2️⃣ Glutaminolysis – Cancer burns glutamine in the mitochondria to make energy, antioxidants, and building blocks
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Many personalized cancer treatments aim to block out-of-control signals that fuel tumor growth. Targeting the PI3K pathway, which drives the growth of many cancers including #breastcancer, has been a challenging goal for researchers. Anwesha Dey, Senior Director & Scientist in Discovery Oncology at Genentech, uses everyday objects to explain how discoveries are enabling a new scientific advancement which not only blocks mutated signals, but also destroys the mutated proteins. | Genentech
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Many cancer treatments aim to block uncontrolled signals that cause tumor growth. But in breast cancer, some signals like PI3K have been challenging to target, making them a key focus for researchers. Anwesha Dey, Senior Director & Scientist in Discovery Oncology at our company uses everyday objects to explain a recent discovery from Genentech scientists, opening up exciting possibilities for personalized cancer care. Learn more and watch the full video series: http://spr.ly/6184sPZW0 | Genentec
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Targeted Therapies for PI3K/AKT Pathway Mutations in Breast Cancer
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🍑 The Fruit That Makes Cancer Cells Self-Destruct 💥 Scientists have discovered that the humble plum may hold extraordinary anti-cancer powers. In a recent Springer Nature study, researchers found that compounds in plums — especially quercitrin — can trigger apoptosis, or cell suicide, in human lung cancer cells. 🧬 Here’s how it works: these polyphenols boost the Bax/Bcl-2 ratio, a key signal that tells cancer cells to self-destruct. Even more impressive, at higher doses, plum extracts outperf
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